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There's a
secret war being waged in the homes and neighborhoods of Earth that the humans
don't even know about; an eternal struggle between two great armies: the Cats
and the Dogs. The film follows a Cat's plan to destroy a new vaccine, that if
developed, would destroy all human allergies to Dogs, and the Dogs' efforts to
stop the Cats. Specifically, it's the story of a young pup (Tobey Maguire)
whose job it is to guard the vaccine. Other dogs include a wise older dog who
watches out for him (Susan Sarandon), a large friendly dog (Michael Clarke
Duncan), and a small dog who serves as an electronics expert (Joe Pantoliano).
Jeff Goldblum is the human scientist that invented the vaccine.
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